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Product Name | Plantanone B |
Price: | $570 / 5mg |
Catalog No.: | CN04422 |
CAS No.: | 55780-30-8 |
Molecular Formula: | C33H40O20 |
Molecular Weight: | 756.7 g/mol |
Purity: | >=98% |
Type of Compound: | Flavonoids |
Physical Desc.: | Powder |
Source: | The seeds of Camellia oleifera Abel |
Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
SMILES: |
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Description | Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1]. |
Target | Ovine COX-1:21.78±0.2 μM (IC50) Ovine COX-2:44.01±0.42 μM (IC50) |
In Vitro | The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1]. Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1]. .Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1]. |