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Soyasaponin II
| Product Name | Soyasaponin II |
| Price: | Inquiry |
| Catalog No.: | CN07499 |
| CAS No.: | 55319-36-3 |
| Molecular Formula: | C47H76O17 |
| Molecular Weight: | 913.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The seeds of Glycine max |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@@]1(C)[C@H](CC[C@]2([C@H]1CC[C@@]1([C@@H]2CC=C2[C@@]1(C)CC[C@@]1([C@H]2CC(C[C@H]1O)(C)C)C)C)C)O[C@@H]1O[C@H](C(=O)O)[C@H]([C@@H]([C@H]1O[C@@H]1OC[C@@H]([C@@H]([C@H]1O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O)O)O)O |
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| Description | Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure[1][2]. |
| Target | HSV-1:54 μM (IC50) HIV-1:112 μM (IC50) influenza virus:88 μM (IC50) HCMV:104 μM (IC50) NLRP3 inflammasome |
| In Vitro | Soyasaponin II inhibits the replication of HSV-1 (IC50=54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM)[1]. |
| In Vivo | Soyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response[2]. |
| Exact Mass | 912.50800 |
| PSA | 274.75000 |
| LogP | 1.34370 |