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Muscone
| Product Name | Muscone |
| Price: | $46 / 20mg |
| Catalog No.: | CN06725 |
| CAS No.: | 541-91-3 |
| Molecular Formula: | C16H30O |
| Molecular Weight: | 238.42 g/mol |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Oil |
| Source: | Mosochus Bersxoxskii Fleror |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC1CCCCCCCCCCCCC(=O)C1 |
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| Description | Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate[1]. |
| Target | NF-κB NLRP3 TNF-α IL-1β IL-6 |
| In Vitro | Muscone significantly downregulates the levels of LPS-induced inflammatory cytokines and inhibits NF-κB and NLRP3 inflammasome activation in Bone marrow-derived macrophages (BMDMs). Muscone serves as a promising and effective drug for post-myocardial infarction (MI) treatment[1]. |
| Density | 0.8±0.1 g/cm3 |
| Boiling Point | 329.5±10.0 °C at 760 mmHg |
| Flash Point | 145.3±11.3 °C |
| Exact Mass | 238.229660 |
| PSA | 17.07000 |
| LogP | 6.33 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Storage condition | -20°C |