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Pterostilbene
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Product Name Pterostilbene
Price: $31 / 20mg
Catalog No.: CN03917
CAS No.: 537-42-8
Molecular Formula: C16H16O3
Molecular Weight: 256.30 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Dracaena cochinchinensis (Lour.) S. C. Chen
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: COc1cc(/C=C/c2ccc(cc2)O)cc(c1)OC
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Description Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].
In Vitro Pterostilbene (0, 5, 25, 50, 100, 200 and 400 µM) shows inhibitory activity against the growth of HeLa cells, with IC50s of 101.2 µM and 65.9 µM at 24 and 48 hrs, respectively. Ipterostilbene (0, 25, 100 and 200 µM) also induces the apoptosis HeLa cells[2]. Pterostilbene (0.05, 0.1, 0.15 and 0.2 mM) has high anti-oxidant activity against DPPH, ABTS, hydroxyl, superoxide, hydrogen peroxide in a dose-dependent manner. Pterostilbene decreases lipid peroxides and hydroperoxides, reduces protein carbonyl groups and restores protein sulphydryl groups in response to damage by TBHP and As-Fe2+. Pterostilbene also inhibits single strand breaks in pBR322[4].
In Vivo Pterostilbene (30 mg/kg daily, p.o. for 21 days) inhibits reactive oxygen species production in the animal model of inflammation[3].
Density1.2±0.1 g/cm3
Boiling Point420.5±35.0 °C at 760 mmHg
Flash Point208.1±25.9 °C
Exact Mass256.109955
PSA38.69000
LogP4.13
Vapour Pressure0.0±1.0 mmHg at 25°C
Storage condition2-8°C