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Coixol
| Product Name | Coixol |
| Price: | $77 / 10mg |
| Catalog No.: | CN01853 |
| CAS No.: | 532-91-2 |
| Molecular Formula: | C8H7NO3 |
| Molecular Weight: | 165.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The seeds of Coix lacryma-jobi L. var. meyuan (Romen.) Stapf. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1ccc2c(c1)oc(=O)[nH]2 |
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| Description | Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen.IC50 value:Target:In vitro: Confluent NCI-H292 cells were pretreated with oleic acid, linoleic acid, glyceryl trilinoleate, beta-stigmasterol or coixol for 30 min and then stimulated with PMA (phorbol 12-myristate 13-acetate), EGF (epidermal growth factor) or TNF-α (tumor necrosis factor-α) for 24 h. Coixol inhibited the expression of MUC5AC mucin gene and production of MUC5AC mucin protein, induced by EGF or TNF-α from NCI-H292 cells; Coixol decreased PMA-induced MUC5AC mucin secretion from NCI-H292 cells [1]. βTC-6 cells were incubated in 2 mM and 20 mM glucose in thepresence of coixol (200 μM) for 60 min at 37°C in Krebs-RingerBicarbonate buffer. Decreased insulin staining was observed by coixol at 20 mM glucose (bottom) suggest that coixol stimulated insulin secretion at high glucose concentration [2].In vivo: |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 292.97°C (rough estimate) |
| Exact Mass | 165.042587 |
| PSA | 55.23000 |
| LogP | 1.07 |
| Storage condition | 2-8°C |