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6-(Furfurylamino)purine
| Product Name | 6-(Furfurylamino)purine |
| Price: | $31 / 20mg |
| Catalog No.: | CN00681 |
| CAS No.: | 525-79-1 |
| Molecular Formula: | C10H9N5O |
| Molecular Weight: | 215.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | c1coc(c1)CNc1[nH]cnc2c1ncn2 |
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| Description | Kinetin (N6-furfuryladenine) belongs to a group of plant growth hormones involved in cell division, differentiation and other physiological processes.IC50 Value: Target:Kinetin is one of the widely used components in numerous skin care cosmetics and cosmeceuticals, such as Valeant products kinerase. Recently, kinetin has the potential to be a treatment for the human splicing disease familial dysautonomia.in vitro: Kinetin-induced cell death reflected by the morphological changes of nuclei including their invagination, volume increase, chromatin condensation and degradation as well as formation of micronuclei showed by AO/EB and 4,6-diamidino-2-phenylindol staining was accompanied by changes including increase in conductivity of cell electrolytes secreted to culture media, decrease in the number of the G1- and G2-phase cells and appearance of fraction of hypoploid cells as the effect of DNA degradation without ladder formation [1]. The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured FD cells [3].in vivo: Subjects received 23.5 mg/Kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant (p = 0.002) [2].Toxicity: On mice with leukaemia P388, kinetin has no effect on the tumour growth, and it appears to be toxic at the dose of 25 mg/kg [4]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 367.6±52.0 °C at 760 mmHg |
| Flash Point | 176.1±30.7 °C |
| Exact Mass | 215.080704 |
| PSA | 79.63000 |
| LogP | -0.56 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Storage condition | −20°C |