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Anisatin
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Product Name Anisatin
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Catalog No.: CN09011
CAS No.: 5230-87-5
Molecular Formula: C15H20O8
Molecular Weight: 328.3 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The fruits of Illicium verum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM[1].
In Vitro Anisatin inhibits [3H]diazepam binding enhanced by either GABA or pentobarbital, without affecting the basal specific binding to rat brain membranes[1].
In Vivo In mice, the LD50 reported for anisatin ranges from 0.76 to 1 mg/kg (po and ip)[1].
Density1.149g/cm3
Boiling Point251.2ºC at 760 mmHg
Flash Point106.7ºC
Exact Mass328.11600
PSA133.52000
Storage condition?20°C