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Physcion
| Product Name | Physcion |
| Price: | $23 / 20mg |
| Catalog No.: | CN05984 |
| CAS No.: | 521-61-9 |
| Molecular Formula: | C16H12O5 |
| Molecular Weight: | 284.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Anthraquinones |
| Physical Desc.: | Yellow powder |
| Source: | The roots and rhizomes of Rheum palmatum L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(O)c2c(c1)C(=O)c1c(C2=O)c(O)cc(c1)C |
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| Description | Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively[1][2]. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[2]. |
| Target | IC50: 38.5 μM (6-phosphogluconate dehydrogenase)[1] Kd: 26.0 μM (6-phosphogluconate dehydrogenase)[1] |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 560.5±50.0 °C at 760 mmHg |
| Flash Point | 215.4±23.6 °C |
| Exact Mass | 284.068481 |
| PSA | 83.83000 |
| LogP | 5.20 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Storage condition | -20°C Freezer, Under Inert Atmosphere |