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Tyramine
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Product Name Tyramine
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Catalog No.: CN00964
CAS No.: 51-67-2
Molecular Formula: C8H11NO
Molecular Weight: 137.18 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Uncaria rhynchophylla.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: NCCc1ccc(cc1)O
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Description Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals.
Target Human Endogenous Metabolite
In Vitro Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals[1]. Tyramine potentiates the postsynaptic inhibitory effects of norepinephrine on the firing of cortical neurones in the rat[2]. Although tyramine exists in three isomerie forms, the orthoisomer and metaisomers are present in very low concentrations and it is the paraisomer that is implied when reference is made to tyramine. The tyramines are generally present in nanogram/gram concentrations in brain tissue, but they have a very rapid turnover. The CNS role of tyramine is unclear, it has been suggested that it is involved in the modulation of dopamine synthesis and may also regulate norepinephrine turnover[3].
Density1.1±0.1 g/cm3
Boiling Point275.1±23.0 °C at 760 mmHg
Flash Point141.3±13.3 °C
Exact Mass137.084061
PSA46.25000
LogP1.38
Vapour Pressure0.0±0.6 mmHg at 25°C
Storage conditionRefrigerator, Under Inert Atmosphere