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Verminoside
| Product Name | Verminoside |
| Price: | Inquiry |
| Catalog No.: | CN03143 |
| CAS No.: | 50932-19-9 |
| Molecular Formula: | C24H28O13 |
| Molecular Weight: | 524.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Iridoids |
| Physical Desc.: | Powder |
| Source: | The barks of Kigelia pinnata |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: |
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| Description | Verminoside is an iridoid isolated from Kigelia africana, exhibits anti-inflammatory and remarkable antioxidant activity with a radical-scavenging activity of 2.5 μg/mL. The genotoxicity of Verminoside on human lymphocytes is associated with elevated levels of PARP-1 and p53 proteins[1][2][3]. |
| Target | PARP-1 |
| In Vitro | Verminoside (Compound 1; 0.01-1 mM; 25 hours; J774.A1 macrophages) treatment shows significant and concentration-related inhibition of iNOS expression at 0.1 mM and 1 mM in LPS-stimulated J774.A1 macrophages[1]. Western Blot Analysis[1] Cell Line: J774.A1 macrophages Concentration: 0.01 mM, 0.1 mM or 1 mM Incubation Time: 25 hours Result: Showed significant and concentration-related inhibition of iNOS expression at 0.1 mM and 1 mM in LPS-stimulated J774.A1 macrophages. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 739.1±60.0 °C at 760 mmHg |
| Flash Point | 253.2±26.4 °C |
| Exact Mass | 492.163147 |
| PSA | 208.13000 |
| LogP | -1.81 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |