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Polyphyllin D
| Product Name | Polyphyllin D |
| Price: | $92 / 20mg |
| Catalog No.: | CN02476 |
| CAS No.: | 50773-41-6 |
| Molecular Formula: | C44H70O16 |
| Molecular Weight: | 855.02 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The rhizomes of Paris yunnanensis Franch. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1O[C@@H](O[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3CC[C@]3([C@H]4C[C@H]4[C@@H]3[C@H](C)[C@]3(O4)CC[C@H](CO3)C)C)C2)C)[C@@H]([C@H]([C@@H]1O[C@@H]1O[C@H]([C@@H]([C@H]1O)O)CO)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O |
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| Description | Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis[1][2][3]. |
| Target | JNK signaling[2] PDK1/Akt/mTOR signaling[3] |
| Density | 1.4±0.1 g/cm3 |
| Exact Mass | 854.466370 |
| PSA | 235.68000 |
| LogP | 7.12 |