Home
Products
Cucurbitacin IIb
| Product Name | Cucurbitacin IIb |
| Price: | Inquiry |
| Catalog No.: | CN07758 |
| CAS No.: | 50298-90-3 |
| Molecular Formula: | C30H48O7 |
| Molecular Weight: | 520.70 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The rhizomes of Hemsleya amabilis Diels. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | OC1CC2C(=CCC3C2(C)C(=O)CC2(C3(C)CC(C2C(C(=O)CCC(O)(C)C)(O)C)O)C)C(C1O)(C)C |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1]. |
| Density | 1.22±0.1 g/cm3 |
| Boiling Point | 668.4±55.0 °C at 760 mmHg |
| Flash Point | 372.0±28.0 °C |
| Exact Mass | 520.340027 |
| PSA | 135.29000 |
| LogP | 1.92 |
| Vapour Pressure | 0.0±4.6 mmHg at 25°C |
| Storage condition | 2-8°C |