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Phloretic acid
| Product Name | Phloretic acid |
| Price: | Inquiry |
| Catalog No.: | CN03739 |
| CAS No.: | 501-97-3 |
| Molecular Formula: | C9H10O3 |
| Molecular Weight: | 166.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The resin of Boswellia carterii Birdw. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | OC(=O)CCc1ccc(cc1)O |
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| Description | Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. |
| Target | Human Endogenous Metabolite |
| In Vivo | Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice[1]. |
| Animal Admin | Mice[1] Indicated mice receive 200 mM Desaminotyrosine dissolved in Kool-Aid in the drinking water (control animals receive Kool-Aid alone). Indicated mice receive poly(IC) injections of 1 mg/kg for vancomycin, neomycin, ampicillin, and metronidazole (VNAM) treated mice or 5 mg/kg for all other mice intraperitoneally daily for 4 days, and then mice are scarified on day five at which time serum is collected[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 352.4±17.0 °C at 760 mmHg |
| Flash Point | 181.1±17.4 °C |
| Exact Mass | 166.062988 |
| PSA | 57.53000 |
| LogP | 1.10 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Storage condition | 2-8°C |