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Olivetol
| Product Name | Olivetol |
| Price: | Inquiry |
| Catalog No.: | CN03929 |
| CAS No.: | 500-66-3 |
| Molecular Formula: | C11H16O2 |
| Molecular Weight: | 180.24 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The leaves of Grevillea robusta. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CCCCCc1cc(O)cc(c1)O |
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| Description | Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively[1][2]. |
| Target | IC50: 7.21 μM (CYP2D6)[2], 15.3 μM (CYP2C19)[1] Ki: 2.71 μM (CYP2C19)[1], 2.87 μM (CYP2D6)[2] CB1, CB2[3] |
| In Vitro | Olivetol inhibits the (S)-mephenytoin 4'-hydroxylase activity of CYP2C19 activity with an IC50 of 15.3 μM and a Ki of 2.71 μM[1]. Olivetol also inhibits AMMC O-demethylase activity of recombinant CYP2D6 with an IC50 of 7.21 μM and a Ki of 2.87 μM[2]. Olivetol is a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 313.3±12.0 °C at 760 mmHg |
| Flash Point | 148.8±14.2 °C |
| Exact Mass | 180.115036 |
| PSA | 40.46000 |
| LogP | 3.35 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Storage condition | Refrigerator |