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Guvacine
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Product Name Guvacine
Price: $103 / 20mg
Catalog No.: CN00735
CAS No.: 498-96-4
Molecular Formula: C6H9NO2
Molecular Weight: 127.14 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The fruits of Areca catechu
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: OC(=O)C1=CCCNC1
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Description Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
Target IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1]
Density1.2±0.1 g/cm3
Boiling Point280.8±35.0 °C at 760 mmHg
Flash Point123.6±25.9 °C
Exact Mass127.063332
PSA49.33000
LogP0.72
Vapour Pressure0.0±1.2 mmHg at 25°C