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Tigloyltropeine
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Product Name Tigloyltropeine
Price: Inquiry
Catalog No.: CN01679
CAS No.: 495-83-0
Molecular Formula: C13H21NO2
Molecular Weight: 223.31 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Oil
Source: The seeds of Datura ferox.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Tigloidin is an analogue of atropine, with anticholinergic activity.
In Vivo Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1].
Density1.06g/cm3
Boiling Point290.2ºC at 760 mmHg
Flash Point99.9ºC
Exact Mass223.15700
PSA29.54000
LogP2.05890
Vapour Pressure0.0021mmHg at 25°C
Storage condition2-8℃