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Product Name | Tigloyltropeine |
Price: | Inquiry |
Catalog No.: | CN01679 |
CAS No.: | 495-83-0 |
Molecular Formula: | C13H21NO2 |
Molecular Weight: | 223.31 g/mol |
Purity: | >=98% |
Type of Compound: | Alkaloids |
Physical Desc.: | Oil |
Source: | The seeds of Datura ferox. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Tigloidin is an analogue of atropine, with anticholinergic activity. |
In Vivo | Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1]. |
Density | 1.06g/cm3 |
Boiling Point | 290.2ºC at 760 mmHg |
Flash Point | 99.9ºC |
Exact Mass | 223.15700 |
PSA | 29.54000 |
LogP | 2.05890 |
Vapour Pressure | 0.0021mmHg at 25°C |
Storage condition | 2-8℃ |