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Robinetin
| Product Name | Robinetin |
| Price: | Inquiry |
| Catalog No.: | CN05341 |
| CAS No.: | 490-31-3 |
| Molecular Formula: | C15H10O7 |
| Molecular Weight: | 302.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The leaves of Robinia pseudacacia |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | Oc1ccc2c(c1)oc(c(c2=O)O)c1cc(O)c(c(c1)O)O |
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| Description | Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation[1][2][3][4][5]. |
| In Vitro | Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner[1]. Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus[2]. Robinetin (100-200 or 25 μM; 1 or 72 h) inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency[3]. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore[3]. |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 669.9±55.0 °C at 760 mmHg |
| Flash Point | 258.6±25.0 °C |
| Exact Mass | 302.042664 |
| PSA | 131.36000 |
| LogP | 2.55 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |