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(-)-Cinchonidine
| Product Name | (-)-Cinchonidine |
| Price: | Inquiry |
| Catalog No.: | CN00685 |
| CAS No.: | 485-71-2 |
| Molecular Formula: | C19H22N2O |
| Molecular Weight: | 294.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | C=CC1CN2CCC1CC2C(c1ccnc2c1cccc2)O |
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| Description | Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities[1]. |
| Target | Ki: 330 μM (dSERT), 4.2 μM (hSERT), 36 μM (hSERT I172M), 196 μM (hSERT S438T), 15 μM (hSERT Y95F) [1] |
| In Vitro | Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively[1]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 464.5±30.0 °C at 760 mmHg |
| Flash Point | 234.7±24.6 °C |
| Exact Mass | 294.173218 |
| PSA | 36.36000 |
| LogP | 3.35 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |