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Product Name Dictamnine
Price: $77 / 20mg
Catalog No.: CN02147
CAS No.: 484-29-7
Molecular Formula: C12H9NO2
Molecular Weight: 199.21 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The root barks of Dictamnus dasycarpus Turcz.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: COc1c2ccccc2nc2c1cco2
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Description Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi.IC50 value:Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) value of 64 microg/ml [1]. Dic induced S phase cell cycle arrest at low concentration and cell apoptosis at high concentration in which loss of mitochondrial membrane potential (Δψmm) was not involved. In addition, inhibition of caspase-3 using the specific inhibitor, z-DQMD-fmk, did not attenuate Dic-induced apoptosis, implying that Dic-induced caspase-3-independent apoptosis [2].
Density1.3±0.1 g/cm3
Boiling Point343.2±22.0 °C at 760 mmHg
Flash Point161.4±22.3 °C
Exact Mass199.063324
PSA35.26000
LogP2.94
Vapour Pressure0.0±0.7 mmHg at 25°C
Storage condition-20℃