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Ajmalicine
| Product Name | Ajmalicine |
| Price: | $31 / 20mg |
| Catalog No.: | CN01973 |
| CAS No.: | 483-04-5 |
| Molecular Formula: | C21H24N2O3 |
| Molecular Weight: | 352.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Cryst. |
| Source: | The herbs of Catharanthus roseus |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COC(=O)C1=CO[C@H]([C@@H]2[C@@H]1C[C@@H]1N(C2)CCc2c1[nH]c1c2cccc1)C |
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| Description | Ajmalicine (Raubasine) is found in herbs of Catharanthus roseus, is an antihypertensive drug used in the treatment of high blood pressure, decreases peripheral resistance and blood pressure[1].Ajmalicine (Raubasine) is an adrenolytic drug which preferentially blocks alpha 1-adrenoceptor than alpha 2-adrenoceptor[2].Ajmalicine (Raubasine) is an reversible non-competitive nicotine receptor antagonist with an IC50 of 72.3 μM[3].Ajmalicine (Raubasine) acts preferentially at postsynaptic sites, competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptor with a pA2 value of 6.57, blocks the inhibitory effect of clonidine with an pA2 value of 6.2[4]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 524.0±50.0 °C at 760 mmHg |
| Flash Point | 270.7±30.1 °C |
| Exact Mass | 352.178680 |
| PSA | 54.56000 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |