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Pinocembrin
| Product Name | Pinocembrin |
| Price: | Inquiry |
| Catalog No.: | CN05353 |
| CAS No.: | 480-39-7 |
| Molecular Formula: | C15H12O4 |
| Molecular Weight: | 256.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The fruits of Alpinia katsunadia Hayata. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | Oc1cc2O[C@@H](CC(=O)c2c(c1)O)c1ccccc1 |
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| Description | Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1]. |
| In Vitro | Pinocembrin (5, 10, 25, 50, 100 or 200 µM, 24 hours) significantly reduces cell viability of RBL-2H3 cells[1]. Pinocembrin (25 or 50 µM) suppresses iNOS, PGE-2 and COX-2 levels, increases p38-Mapk and IкB-α, and inhibits phosphorylation of IкB-α[1]. Cell Viability Assay[1] Cell Line: RBL-2H3 cells Concentration: 5, 10, 25, 50, 100 or 200 µM Incubation Time: 24 hours Result: Decreased cell viability by ∼50% at ≥ 100 µM. Showed 75% cell viability at lower concentrations. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 511.1±50.0 °C at 760 mmHg |
| Flash Point | 199.3±23.6 °C |
| Exact Mass | 256.073547 |
| PSA | 66.76000 |
| LogP | 3.93 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |