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Bergenin
| Product Name | Bergenin |
| Price: | $12 / 20mg |
| Catalog No.: | CN04028 |
| CAS No.: | 477-90-7 |
| Molecular Formula: | C14H16O9 |
| Molecular Weight: | 328.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The herbs of Bergenia purpurascens |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | OC[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]1O)O)OC(=O)c1c2c(O)c(c(c1)O)OC |
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| Description | Bergenin, a polyphenol, is a potent antinarcotic agent with antioxidant action. IC50 value: < 2.5 μM (antiplasmodial) [3]Target:In vitro: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver [2].In vivo: Bergenin attenuated inflammatory cell infiltration and decreased the concentration of NO, TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis [1]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 658.9±55.0 °C at 760 mmHg |
| Flash Point | 250.7±25.0 °C |
| Exact Mass | 328.079437 |
| PSA | 145.91000 |
| LogP | 0.05 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Storage condition | ?20°C |