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Liriodenine
| Product Name | Liriodenine |
| Price: | Inquiry |
| Catalog No.: | CN01989 |
| CAS No.: | 475-75-2 |
| Molecular Formula: | C17H9NO3 |
| Molecular Weight: | 275.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The barks of Liriodendron chinense (Hemsl.) Sarg. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities[1]. Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9[2]. |
| In Vitro | Liriodenine is against P-388, KB, HT-29, MCF-7, A549, ASK and Hek-293 cells with IC50 values of 9.60 μM, 11.02 μM, 10.62 μM, 9.20 μM and 8.07μM, respectively. |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 531.0±19.0 °C at 760 mmHg |
| Flash Point | 275.0±21.5 °C |
| Exact Mass | 275.058258 |
| PSA | 48.42000 |
| LogP | 3.30 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |