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Campesterol
| Product Name | Campesterol |
| Price: | $161 / 10mg |
| Catalog No.: | CN02456 |
| CAS No.: | 474-62-4 |
| Molecular Formula: | C28H48O |
| Molecular Weight: | 400.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The seeds of Brassica campestris |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC([C@@H](CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2[C@]1(C)CC=C(C2)O)C)C)C |
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| Description | Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects. |
| In Vitro | Campesterol shows a weak cytotoxicity in non-proliferating human umbilical vein endothelial cells (HUVECs). Within the non-cytotoxic concentration range, campesterol significantly inhibits the bFGF-induced proliferation and tube formation of HUVECs in a concentration-dependent manner, while it does not affect the motility of HUVECs. 50 μg/mL of campesterol decreases the cell viability up to about 56% of control(IC50 of over 50 μg/mL)[1]. |
| In Vivo | Campesterol effectively disrupts the bFGF-induced neovascularization in chick chorioallantoic membrane (CAM) in vivo[1]. |
| Cell Assay | The effect of campesterol on the viable cell number was assessed by XTT assay. HUVECs were treated with various concentrations (10, 20, 30, 40 and 50 μg/mL) of campesterol and incubated at 37 °C in a humidified incubator for 24 h, a XTT working solution was added to each well. The cells were incubated at 37 °C for 2 h and the optical density was measured using a microplate reader at 450 nm[1]. |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 489.5±14.0 °C at 760 mmHg |
| Flash Point | 214.3±12.4 °C |
| Exact Mass | 400.370514 |
| PSA | 20.23000 |
| LogP | 10.20 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Storage condition | -20°C |