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alpha-Cyperone
| Product Name | alpha-Cyperone |
| Price: | $77 / 20mg |
| Catalog No.: | CN09516 |
| CAS No.: | 473-08-5 |
| Molecular Formula: | C15H22O |
| Molecular Weight: | 218.33 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Oil |
| Source: | The rhizomes of Cyperus rotundus L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=C)[C@@H]1CC[C@@]2(C(=C(C)C(=O)CC2)C1)C |
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| Description | Alpha-cyperone is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. which would be highly beneficial for treatment of inflammatory diseases such as AD.In vitro: The anti-inflammatory activity of alpha-cyperone is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells.[1]Alpha-Cyperone binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter. [2] |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 320.4±22.0 °C at 760 mmHg |
| Flash Point | 142.8±13.2 °C |
| Exact Mass | 218.167068 |
| PSA | 17.07000 |
| LogP | 4.22 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Storage condition | -20°C |