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3-O-(2'E,4'E-Decadienoyl)ingenol
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Product Name 3-O-(2'E,4'E-Decadienoyl)ingenol
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Catalog No.: CN08555
CAS No.: 466663-11-6
Molecular Formula: C30H42O6
Molecular Weight: 498.7 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The roots of Euphorbia kansui T. N. Liou ex S. B. Ho
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description 3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively[1].
In Vitro 3-O-(2'E,4'E-Decadienoyl)-ingenol(5-30 μg/mL;24 小时)显示出对人类正常细胞系 L-O2 和 GES-1 的细胞毒性,具有剂量依赖关系 [1]。 Cell Cytotoxicity Assay[1] Cell Line: L-O2 and GES-1 cells Concentration: 5 μg/mL, 10 μg/mL,15 μg/mL, 20 μg/mL, 25 μg/mL, 30 μg/mL Incubation Time: 24 hours Result: Showed cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships.
Density1.2±0.1 g/cm3
Boiling Point635.6±55.0 °C at 760 mmHg
Flash Point201.7±25.0 °C
Exact Mass498.298126
LogP7.30
Vapour Pressure0.0±4.2 mmHg at 25°C