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Product Name | 3-O-(2'E,4'E-Decadienoyl)ingenol |
Price: | Inquiry |
Catalog No.: | CN08555 |
CAS No.: | 466663-11-6 |
Molecular Formula: | C30H42O6 |
Molecular Weight: | 498.7 g/mol |
Purity: | >=98% |
Type of Compound: | Diterpenoids |
Physical Desc.: | Powder |
Source: | The roots of Euphorbia kansui T. N. Liou ex S. B. Ho |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | 3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively[1]. |
In Vitro | 3-O-(2'E,4'E-Decadienoyl)-ingenol(5-30 μg/mL;24 小时)显示出对人类正常细胞系 L-O2 和 GES-1 的细胞毒性,具有剂量依赖关系 [1]。 Cell Cytotoxicity Assay[1] Cell Line: L-O2 and GES-1 cells Concentration: 5 μg/mL, 10 μg/mL,15 μg/mL, 20 μg/mL, 25 μg/mL, 30 μg/mL Incubation Time: 24 hours Result: Showed cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. |
Density | 1.2±0.1 g/cm3 |
Boiling Point | 635.6±55.0 °C at 760 mmHg |
Flash Point | 201.7±25.0 °C |
Exact Mass | 498.298126 |
LogP | 7.30 |
Vapour Pressure | 0.0±4.2 mmHg at 25°C |