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Proscillaridin A
| Product Name | Proscillaridin A |
| Price: | Inquiry |
| Catalog No.: | CN02291 |
| CAS No.: | 466-06-8 |
| Molecular Formula: | C30H42O8 |
| Molecular Weight: | 530.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Steroids |
| Physical Desc.: | Powder |
| Source: | The herbs of Drimia robusta |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | O[C@H]1[C@H](O[C@H]2CC[C@]3(C(=C2)CC[C@@H]2[C@@H]3CC[C@]3([C@]2(O)CC[C@@H]3c2ccc(=O)oc2)C)C)O[C@H]([C@@H]([C@H]1O)O)C |
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| Description | Proscillaridin A is a potent poison of topoisomerase I/II activity with IC50 values of 30 nM and 100 nM, respectively[1]. |
| Target | Topoisomerase I:30 nM (IC50) Topoisomerase II:100 nM (IC50) |
| In Vitro | Proscillaridin A (0-160 nM; 48 hours) reveals the antiproliferative response in a time- as well as dose-dependent manner in MCF-7 cells[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 716.7±60.0 °C at 760 mmHg |
| Flash Point | 232.6±26.4 °C |
| Exact Mass | 530.287964 |
| PSA | 129.59000 |
| LogP | 3.90 |
| Vapour Pressure | 0.0±5.2 mmHg at 25°C |
| Storage condition | 2-8℃ |