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(-)-Borneol
| Product Name | (-)-Borneol |
| Price: | $15 / 20mg |
| Catalog No.: | CN09597 |
| CAS No.: | 464-45-9 |
| Molecular Formula: | C10H18O |
| Molecular Weight: | 154.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Monoterpenoids |
| Physical Desc.: | Powder |
| Source: | The fruits of Cnidium monnieri |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O[C@@H]1C[C@H]2C([C@]1(C)CC2)(C)C |
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| Description | (-)-Borneol has a highly efficacious positive modulating action at GABA receptor with an EC50 of 237 μM. |
| Target | EC50: 237 μM (GABA receptor)[1] |
| In Vitro | (-)-Borneol is an enantiomer of (+)-Borneol. (+)-Borneol is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM. At high concentrations (>1.5 mM), (-)-Borneol directly activates GABAA receptors producing 84% of the maximal GABA response indicative of a weak partial agonist action. (-)-Borneol produces dose-dependent positive modulation of the Cl- conductance generated by extremely low dose GABA at α1β2γ2L GABAA receptors[1]. |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 212.0±0.0 °C at 760 mmHg |
| Flash Point | 65.6±0.0 °C |
| Exact Mass | 154.135757 |
| PSA | 20.23000 |
| LogP | 2.71 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |