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Linolenic acid
| Product Name | Linolenic acid |
| Price: | $31 / 20mg |
| Catalog No.: | CN06438 |
| CAS No.: | 463-40-1 |
| Molecular Formula: | C18H30O2 |
| Molecular Weight: | 278.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Oil |
| Source: | The herbs of Fructus Perillae |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC/C=CC/C=CC/C=CCCCCCCCC(=O)O |
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| Description | α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1]. |
| Target | PI3K Akt |
| In Vitro | α-Linolenic acid converses into the longer chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)[1]. |
| In Vivo | α-Linolenic acid (50, 100, 250 mg/kg; for 10 days) can completely inhibit collagen- and adrenaline-induced thrombosis in mice at 250 mg/kg[1]. α-Linolenic acid (35, 70, 175 mg/kg) suppresses A-V thrombus formation in rats (weighing at 250 ~ 300 g)[1]. α-Linolenic acid (70 or 175 mg/kg) inhibits collagen stimulated platelet aggregation in rats[1]. Animal Model: Mice weighing at 18 ~ 22 g[1] Dosage: 50, 100, 250 mg/kg Administration: For 10 days Result: Completely inhibited collagen- and adrenaline-induced thrombosis at 250 mg/kg. |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 443.4±0.0 °C at 760 mmHg |
| Flash Point | 275.7±14.4 °C |
| Exact Mass | 278.224579 |
| PSA | 37.30000 |
| LogP | 6.50 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Storage condition | 2-8°C |