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Ligustilide
| Product Name | Ligustilide |
| Price: | $41 / 20mg |
| Catalog No.: | CN09695 |
| CAS No.: | 4431-01-0 |
| Molecular Formula: | C12H14O2 |
| Molecular Weight: | 190.238 |
| Purity: | >=98% |
| Type of Compound: | Miscellaneous |
| Physical Desc.: | Oil |
| Source: | The roots of Angelica sinensis (Oliv.) Diels. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CCCC=C1OC(=O)C2=C1CCC=C2 |
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| Use of Ligustilide | Ligustilide is an effective constituent extracted from Angelica sinensis.IC50 value:Target:In vitro: To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide [1].In vivo: |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 377.9±11.0 °C at 760 mmHg |
| Flash Point | 158.6±16.7 °C |
| Exact Mass | 190.099380 |
| Melting Point | 297-298ºC |
| Signal Word | Signal Word |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Risk Phrases | 22/23 |
| Safety Phrases | 24/25 |