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Deoxyshikonin
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Product Name Deoxyshikonin
Price: $176 / 10mg
Catalog No.: CN05892
CAS No.: 43043-74-9
Molecular Formula: C16H16O4
Molecular Weight: 272.3 g/mol
Purity: >=98%
Type of Compound: Quinones
Physical Desc.: Powder
Source: The roots of Lithosperraum erythrorhizon Sieb. et Zucc.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: CC(=CCCC1=CC(=O)c2c(C1=O)c(O)ccc2O)C
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Description Deoxyshikonin is isolated from Lithospermum erythrorhizon Sieb with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro[1]. Deoxyshikonin shows significant synergic antimicrobial activity with tetracycline against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA[2].
Density1.3±0.1 g/cm3
Boiling Point503.7±50.0 °C at 760 mmHg
Flash Point272.5±26.6 °C
Exact Mass272.104858
PSA74.60000
LogP4.72
Vapour Pressure0.0±1.3 mmHg at 25°C
Storage condition2-8C