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Product Name | Deoxyshikonin |
Price: | $176 / 10mg |
Catalog No.: | CN05892 |
CAS No.: | 43043-74-9 |
Molecular Formula: | C16H16O4 |
Molecular Weight: | 272.3 g/mol |
Purity: | >=98% |
Type of Compound: | Quinones |
Physical Desc.: | Powder |
Source: | The roots of Lithosperraum erythrorhizon Sieb. et Zucc. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | CC(=CCCC1=CC(=O)c2c(C1=O)c(O)ccc2O)C |
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Description | Deoxyshikonin is isolated from Lithospermum erythrorhizon Sieb with antitumor activity. Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF, indicates a prolymphangiogenesis as well as a proangiogenesis effect in vitro[1]. Deoxyshikonin shows significant synergic antimicrobial activity with tetracycline against S. pneumonia (MIC=17 μg/mL), also shows significantly inhibitory activities against MRSA[2]. |
Density | 1.3±0.1 g/cm3 |
Boiling Point | 503.7±50.0 °C at 760 mmHg |
Flash Point | 272.5±26.6 °C |
Exact Mass | 272.104858 |
PSA | 74.60000 |
LogP | 4.72 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Storage condition | 2-8C |