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Santamarine
| Product Name | Santamarine |
| Price: | Inquiry |
| Catalog No.: | CN09432 |
| CAS No.: | 4290-13-5 |
| Molecular Formula: | C15H20O3 |
| Molecular Weight: | 248.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Sesquiterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Dolomiaea souliei (Franch.) Shih |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
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| Description | Santamarine (Santamarin), a sesquiterpene lactone, increases HO-1 expression through Nrf2 translocation and suppresses NO, PGE2, TNF-α, and IL-1β production through inhibition of NF-κB translocation in LPS-induced macrophages. Santamarine shows anti-photoaging properties via inhibition of MAPK/AP-1 and stimulation of TGF-β/Smad signaling in UVA-irradiated human dermal fibroblasts (HDFs). Antioxidant activities[1][2]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 415.6±45.0 °C at 760 mmHg |
| Flash Point | 176.5±21.5 °C |
| Exact Mass | 248.141251 |
| PSA | 46.53000 |
| LogP | 1.94 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |