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Albiflorin
| Product Name | Albiflorin |
| Price: | $62 / 20mg |
| Catalog No.: | CN09682 |
| CAS No.: | 39011-90-0 |
| Molecular Formula: | C23H28O11 |
| Molecular Weight: | 480.46 g/mol |
| Purity: | >=98% |
| Type of Compound: | Monoterpenoids |
| Physical Desc.: | White powder |
| Source: | The roots of Paeonia albiflora |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1O[C@@H](O[C@@]23C[C@@H]4[C@@]3(COC(=O)c3ccccc3)C(=O)O[C@@]2(C)C[C@H]4O)[C@@H]([C@H]([C@@H]1O)O)O |
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| Description | Albiflorin is a major constituent contained in peony root; possesses therapeutic potential for neurodegenerative diseases.IC50 value:Target: in vitro: Albiflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation, and B-cell lymphoma 2 (Bcl-2)/Bax ratio. Albiflorin also enhanced phosphorylation of AKT and its downstream element glycogen synthase kinase-3β, and this effect was abrogated by the AKT inhibitor LY294002 [1]. in vivo: Mice were exposed to X-ray radiation (400 Roentgen), and both mice and rabbits were intraperitoneally injected with cyclophosphamide (100.0 mg/kg) and cytarabine chloride (92.7 mg/kg), respectively, for 3 days to induce myelosuppression. Albiflorin was subsequently administrated intravenously at low (15.0 mg/kg for mice, 6.00 mg/kg for rabbits), intermediate (30.0 mg/kg for mice, 12.0 mg/kg for rabbits) and high (60.0 mg/kg for mice, 24.0 mg/kg for rabbits) doses, as well as orally (60.0 mg/kg for mice, 24.0 mg/kg for rabbits) for 7 days. Shenqi tablets were used as positive controls (oral administration of 936.0 mg/kg for mice, 336.0 mg/kg for rabbits). The administration of Albiflorin significantly ameliorated myelosuppression in all cases [2]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 722.1±60.0 °C at 760 mmHg |
| Flash Point | 248.9±26.4 °C |
| Exact Mass | 480.163147 |
| PSA | 172.21000 |
| LogP | -0.97 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Storage condition | ?20°C |