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1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane
1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane WeChat WhatsApp
Product Name 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane
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Catalog No.: CN04043
CAS No.: 376362-03-7
Molecular Formula: C21H26O3
Molecular Weight: 326.4 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The branches of Broussonetia papyrifera
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl), isolated from Broussonetia kazinoki, shows in vitro inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 of 13.00 μM. PTP1B is a negative regulator of insulin action and an important mediator in the pathogenesis of insulinresistance and non-insulin dependent diabetes mellitus. PTP1B is regarded as a significant target for type 2 diabetes[1].
Density1.1±0.1 g/cm3
Boiling Point490.3±40.0 °C at 760 mmHg
Flash Point250.3±27.3 °C
Exact Mass326.188202
PSA49.69000
LogP5.74
Vapour Pressure0.0±1.3 mmHg at 25°C