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Isorhamnetin 3-glucuronide
| Product Name | Isorhamnetin 3-glucuronide |
| Price: | Inquiry |
| Catalog No.: | CN04928 |
| CAS No.: | 36687-76-0 |
| Molecular Formula: | C22H20O13 |
| Molecular Weight: | 492.39 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Potentilla discolor Bge. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: |
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| Description | Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase[1]. |
| In Vitro | Isorhamnetin 3-glucuronide (0-100 µM; 48 h) 以剂量依赖的方式对 MCF-7 细胞显示出抗增殖活性[1]。 Isorhamnetin 3-glucuronide (0-100 µM; 48 h) 以剂量依赖性方式诱导细胞凋亡和细胞周期停滞在 S 期[1]。 Cell Proliferation Assay[1] Cell Line: MCF-7 cells Concentration: 0, 25, 50, 100 µM Incubation Time: 48 h Result: Inhibited cell proliferation in a dose-dependent manner. Apoptosis Analysis[1] Cell Line: MCF-7 cells Concentration: 25, 100 µM Incubation Time: 48 h Result: Induced apoptosis with the rate of 16.8%, 49.8% at 25, 100 µM, respectively. Cell Cycle Analysis[1] Cell Line: MCF-7 cells Concentration: 0, 50, 100 µM Incubation Time: 48 h Result: Induced cell cycle arrest at S-phase. |
| Density | 1.83±0.1 g/cm3 |
| Exact Mass | 492.09000 |
| PSA | 216.58000 |