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Octahydrocurcumin
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Product Name Octahydrocurcumin
Price: $351 / 10mg
Catalog No.: CN03768
CAS No.: 36062-07-4
Molecular Formula: C21H28O6
Molecular Weight: 376.44 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The rhizomes of Curcuma longa L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: COc1cc(CCC(CC(CCc2ccc(c(c2)OC)O)O)O)ccc1O
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Description Octahydrocurcumin is a hydrogenated derivatives of curcumin; metabolite of curcumin.IC50 value:Target: OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavenging were tetrahydro-, hexahydro-, and octahydrocurcumin with IC50 values of 10.0, 11.7, and 12.3 microM, respectively [1]. curcumin and tetrahydrocurcumin significantly inhibited the release of prominent cytokines, including tumor necrosis factor?α (TNF?α) and interleukin?6 (IL?6); however, hexahydrocurcumin and octahydrocurcumin did not significantly alter cytokine release [2]. Hydrogenated derivatives of curcumin exhibited stronger DPPH scavenging activity compared to curcumin and a reference antioxidant, trolox. The scavenging activity significantly decreased in the order THC>HHC=OHC>trolox>curcumin>Dmc>>>Bdmc [3].
Density1.2±0.1 g/cm3
Boiling Point623.5±55.0 °C at 760 mmHg
Flash Point330.9±31.5 °C
Exact Mass376.188599
PSA99.38000
LogP1.73
Vapour Pressure0.0±1.9 mmHg at 25°C
Storage condition-20°C