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Dihydrosanguinarine
| Product Name | Dihydrosanguinarine |
| Price: | $204 / 20mg |
| Catalog No.: | CN01170 |
| CAS No.: | 3606-45-9 |
| Molecular Formula: | C20H15NO4 |
| Molecular Weight: | 333.1 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | The herbs of Chelidonium majus. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CN1Cc2c3OCOc3ccc2c2c1c1cc3OCOc3cc1cc2 |
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| Description | Dihydrosanguinarine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal and anticancer activity.IC50 value:Target:in vitro: Dihydrosanguinarine showed much less cytotoxicity than sanguinarine: at the highest concentration tested (20 microM) and 24h exposure, dihydrosanguinarine decreased viability only to 52% [1]. Dihydrosanguinarine showed the highest antifungal activity against B. cinerea Pers, with 95.16% mycelial growth inhibition at 50 μg/ml [2]. dihydrosanguinarine showed the most potent leishmanicidal activities (IC(50) value: 0.014 microg/ml, respectively) [4].in vivo: Repeated dosing of DHSG for 90 days at up to 500 ppm in the diet (i.e. approximately 58 mg/kg/day) showed no evidence of toxicity in contrast to results published in the literature [3]. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 566.9±29.0 °C at 760 mmHg |
| Flash Point | 176.8±21.5 °C |
| Exact Mass | 333.100098 |
| PSA | 40.16000 |
| LogP | 4.68 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Storage condition | 2-8℃ |