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Product Name | Incensole acetate |
Price: | Inquiry |
Catalog No.: | CN08494 |
CAS No.: | 34701-53-6 |
Molecular Formula: | C22H36O3 |
Molecular Weight: | 348.5 g/mol |
Purity: | >=98% |
Type of Compound: | Diterpenoids |
Physical Desc.: | Oil |
Source: | The resin of Boswellia carterii Birdw. |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: | CC(=O)OC1CCC(=CCCC(=CCC2(OC1(C)CC2)C(C)C)C)C |
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Description | Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1]. |
In Vitro | Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25–35-induced cell death, a 48–52% decrease in cell viability at Aβ25–35 is restored to 85–89% upon pre-treatment with IA[1]. Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25–35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells Concentration: 100 μM Incubation Time: Pre-treatment 4 hours Result: Increased hOBNSCs cell viability induced by Aβ 25-35. |
Density | 1.0±0.1 g/cm3 |
Boiling Point | 420.1±45.0 °C at 760 mmHg |
Flash Point | 178.6±23.3 °C |
Exact Mass | 348.266449 |
PSA | 35.53000 |
LogP | 6.83 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Storage condition | -20℃ |