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Tirandamycin A
| Product Name | Tirandamycin A |
| Price: | Inquiry |
| Catalog No.: | CN01804 |
| CAS No.: | 34429-70-4 |
| Molecular Formula: | C22H27NO7 |
| Molecular Weight: | 417.46 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Powder |
| Source: | From Streptomyces sp.SCSIO 1666. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties[1][2]. |
| In Vitro | A 60 μM treatment with Tirandamycin A results in a slightly stronger inhibition, demonstrating a 84.2% reduction in growth of Entamoeba histolytica HM-1:IMSS and 64.8% reduction in growth by Entamoeba histolytica Col. Tirandamycin A inhibits chain initiation and elongation of bacterial RNA polymerase without acting on mammalian polymerases[1]. |
| Density | 1.314g/cm3 |
| Boiling Point | 560.1ºC at 760mmHg |
| Flash Point | 292.5ºC |
| Exact Mass | 417.17900 |
| PSA | 114.46000 |
| LogP | 1.84130 |