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1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
| Product Name | 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one |
| Price: | Inquiry |
| Catalog No.: | CN03660 |
| CAS No.: | 332371-82-1 |
| Molecular Formula: | C19H18O3 |
| Molecular Weight: | 294.35 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenols |
| Physical Desc.: | Powder |
| Source: | The plants of Aframomum letestuianum. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2]. |
| In Vitro | 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 2) (1-10 µM) inhibits melanogenesis in B16 melanoma 4A5 cells with an IC50 of 1.99 µM[2]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 542.0±45.0 °C at 760 mmHg |
| Flash Point | 295.7±25.2 °C |
| Exact Mass | 294.125580 |
| PSA | 57.53000 |
| LogP | 2.89 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |