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Cajanin
| Product Name | Cajanin |
| Price: | Inquiry |
| Catalog No.: | CN05408 |
| CAS No.: | 32884-36-9 |
| Molecular Formula: | C16H12O6 |
| Molecular Weight: | 300.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Kadsura interior |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2]. |
| In Vitro | Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts[2]. Cajanin induces the phosphorylation of both Erk1/2 and Akt[2]. |
| In Vivo | Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levels in all anatomical regions of the skeleton studied in Sprague Dawley rats[1]. |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 605.5±55.0 °C at 760 mmHg |
| Flash Point | 231.7±25.0 °C |
| Exact Mass | 300.063385 |
| PSA | 100.13000 |
| LogP | 3.57 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |