Description |
Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity[1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase[2].
|
Target |
PPARγ
Apoptosis
Aromatase
|
In Vitro |
Aromatase, a cytochrome P450 enzyme, is an important pharmacological target in breast cancer therapy[2].
|
Density | 1.5±0.1 g/cm3 |
Boiling Point | 772.9±60.0 °C at 760 mmHg |
Flash Point | 257.0±26.4 °C |
Exact Mass | 540.184265 |
PSA | 201.67000 |
LogP | -0.91 |
Vapour Pressure | 0.0±2.8 mmHg at 25°C |
Storage condition | room temp |