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Medicarpin
| Product Name | Medicarpin |
| Price: | $380 / 10mg |
| Catalog No.: | CN05411 |
| CAS No.: | 32383-76-9 |
| Molecular Formula: | C16H14O4 |
| Molecular Weight: | 270.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Hedysarum polybotrys Hand. -Mazz. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1ccc2c(c1)O[C@@H]1[C@H]2COc2c1ccc(c2)O |
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| Description | Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs[1]. |
| In Vitro | Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells)[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 418.8±45.0 °C at 760 mmHg |
| Flash Point | 207.1±28.7 °C |
| Exact Mass | 270.089203 |
| PSA | 47.92000 |
| LogP | 2.72 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |