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O-Nornuciferine
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Product Name O-Nornuciferine
Price: $556 / 5mg
Catalog No.: CN00914
CAS No.: 3153-55-7
Molecular Formula: C18H19NO2
Molecular Weight: 281.35 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Nelumbo nucifera Gaertn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: COc1c(O)cc2c3c1c1ccccc1CC3N(CC2)C
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Description O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].
In Vitro O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1]. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].
Density1.2±0.1 g/cm3
Boiling Point451.4±45.0 °C at 760 mmHg
Flash Point226.8±28.7 °C
Exact Mass281.141571
PSA32.70000
LogP3.36
Vapour Pressure0.0±1.1 mmHg at 25°C