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Fargesin
| Product Name | Fargesin |
| Price: | $54 / 20mg |
| Catalog No.: | CN02952 |
| CAS No.: | 31008-19-2 |
| Molecular Formula: | C21H22O6 |
| Molecular Weight: | 370.39 g/mol |
| Purity: | >=98% |
| Type of Compound: | Lignans |
| Physical Desc.: | Cryst. |
| Source: | The flowers of Magnolia biondii Pamp. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(ccc1OC)[C@@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1ccc2c(c1)OCO2 |
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| Description | Fargesin is a bioactive neolignan isolated from magnolia plants，with antihypertensive and anti-inflammatory effects[1][2][3]. |
| In Vitro | Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-ĸB[3]. Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis[4]. |
| In Vivo | Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 506.4±50.0 °C at 760 mmHg |
| Flash Point | 208.9±30.0 °C |
| Exact Mass | 370.141632 |
| PSA | 55.38000 |
| LogP | 3.20 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |