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6,7-Dihydroxycoumarin
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Product Name 6,7-Dihydroxycoumarin
Price: $15 / 20mg
Catalog No.: CN06306
CAS No.: 305-01-1
Molecular Formula: C9H6O4
Molecular Weight: 178.14 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Powder
Source: The peels of Aesculus hippocastanum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: O=c1ccc2c(o1)cc(c(c2)O)O
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Description Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities[1].
Target PI3K Akt
Density1.6±0.1 g/cm3
Boiling Point469.7±45.0 °C at 760 mmHg
Flash Point201.5±22.2 °C
Exact Mass178.026611
PSA70.67000
LogP0.98
Vapour Pressure0.0±1.2 mmHg at 25°C
Storage condition2-8°C