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Oxyresveratrol
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Product Name Oxyresveratrol
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Catalog No.: CN04062
CAS No.: 29700-22-9
Molecular Formula: C14H12O4
Molecular Weight: 244.2 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Dracaena angustifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
SMILES: Oc1ccc(c(c1)O)/C=C/c1cc(O)cc(c1)O
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Description Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM) In vitro: 1)oxyresveratrol exhibited more than 50% inhibition at 100 μM on L-tyrosine oxidation by murine tyrosinase activity.2) oxyresveratrol showed an IC50 value of 52.7 μM on the enzyme activity. 3) oxyresveratrol works through reversible inhibition of tyrosinase activity rather than suppression of the expression and synthesis of the enzyme.[2] In vivo: 1) Oxyresveratrol (10 or 20 mg/kg) significantly reduced the brain infarct volume by approximately 54% and 63%, respectively, when compared to vehicle-treated MCAO rats.2) oxyresveratrol treatment diminished cytochrome c release and decreasedcaspase-3 activation in MCAO rats. [3]
Density1.5±0.1 g/cm3
Boiling Point523.8±30.0 °C at 760 mmHg
Flash Point260.8±19.2 °C
Exact Mass244.073563
PSA80.92000
LogP3.17
Vapour Pressure0.0±1.4 mmHg at 25°C