Home
Products
Pectolinarin
| Product Name | Pectolinarin |
| Price: | $117 / 20mg |
| Catalog No.: | CN05502 |
| CAS No.: | 28978-02-1 |
| Molecular Formula: | C29H34O15 |
| Molecular Weight: | 622.57 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Cirsium japonicum DC. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | COc1c(O[C@@H]2O[C@H](CO[C@@H]3O[C@@H](C)[C@@H]([C@H]([C@H]3O)O)O)[C@H]([C@@H]([C@H]2O)O)O)cc2c(c1O)c(=O)cc(o2)c1ccc(cc1)OC |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | Pectolinarin, isolated from Cirsium chanroenicum, possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2]. |
| Target | IL-6 IL-8 PGE2 NO Apoptosis |
| In Vitro | Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs[2]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 896.4±65.0 °C at 760 mmHg |
| Flash Point | 292.4±27.8 °C |
| Exact Mass | 622.189758 |
| PSA | 227.20000 |
| LogP | 1.71 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Storage condition | 2~8℃ |