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8-Prenylkaempferol
| Product Name | 8-Prenylkaempferol |
| Price: | Inquiry |
| Catalog No.: | CN05058 |
| CAS No.: | 28610-31-3 |
| Molecular Formula: | C20H18O6 |
| Molecular Weight: | 354.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The roots of Sophora flavescens |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=CCc1c(O)cc(c2c1oc(c1ccc(cc1)O)c(c2=O)O)O)C |
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| Description | Desmethylicaritin is a phytoestrogenic molecule, has inducible effect on directional differentiation of embryonic stem cells into cardiomyocytes. Desmethylicaritin also suppresses adipogenesis via Wnt/β-catenin signaling pathway[1][2]. |
| In Vitro | 去甲基菌素是血清中淫羊藿类黄酮的生物活性代谢产物[1]。 去甲基甘草素 (0.1, 1, 10 μM; 48 h) 以剂量依赖的方式抑制 3T3-L1 细胞的脂肪生成并抑制脂肪生成过程中的克隆扩增[1]。 去甲基孢菌素 (10 μM; 48 h) 不影响 CCAAT/增强子结合蛋白 δ 和 β 的 mRNA 的表达，但降低了 CCAAT/增强子结合蛋白 α、过氧化物酶体增殖物激活受体 γ、脂肪细胞脂质结合蛋白和脂蛋白脂肪酶的mRNA表达[1]。 去甲基孢菌素 (10 μM; 2、4、6、10 d) 增加了细胞质和细胞核中 β-catenin 的蛋白表达，免疫荧光结果证实去甲基化菌素增加了 β-catenin 的核转运[1]。 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 605.7±55.0 °C at 760 mmHg |
| Flash Point | 219.2±25.0 °C |
| Exact Mass | 354.110352 |
| PSA | 111.13000 |
| LogP | 4.15 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Storage condition | Refrigerator |