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IVHD-valtrate
| Product Name | IVHD-valtrate |
| Price: | Inquiry |
| Catalog No.: | CN03061 |
| CAS No.: | 28325-56-6 |
| Molecular Formula: | C27H40O11 |
| Molecular Weight: | 540.60 g/mol |
| Purity: | >=98% |
| Type of Compound: | Iridoids |
| Physical Desc.: | Oil |
| Source: | The roots of Valeriana jatamansi Jones. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research[1]. |
| Target | IC50: apoptosis[1] |
| In Vitro | IVHD-valtrate inhibits the growth and proliferation of the A2780 and OVCAR-3 ovarian cancer cell lines in a concentration-dependent manner[1]. IVHD-valtrate results in a relatively low cytotoxicity to immortalized non-tumorigenic human ovarian surface epithelial cells (IOSE-144)[1]. |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 616.5±55.0 °C at 760 mmHg |
| Flash Point | 193.9±25.0 °C |
| Exact Mass | 540.257080 |
| PSA | 147.19000 |
| LogP | 2.95 |
| Vapour Pressure | 0.0±4.0 mmHg at 25°C |